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dc.contributor.authorFlorencio, Melissa Cristina Moraes
dc.date.accessioned2023-12-21T18:42:35Z-
dc.date.available2023-12-21T18:42:35Z-
dc.date.issued2020-03-12
dc.identifier.citationFLORENCIO, Melissa Cristina Moraes. Stomoxys calcitrans: estabelecimento de colônia, caracterização da glândula salivar e interação com patógenos. 2020. 65 f. Tese (Doutorado em Ciências Veterinárias) - Instituto de Veterinária, Universidade Federal Rural do Rio de Janeiro, Seropédica, RJ, 2020.por
dc.identifier.urihttps://rima.ufrrj.br/jspui/handle/20.500.14407/9680-
dc.description.abstractStomoxys calcitrans, conhecida como mosca-dos-estábulos é um díptero de grande importância médico veterinária. Machos e fêmeas se alimentam de sangue, hábito parasita que tem como consequência prejuízos nos ambientes de animais de criação. Os desdobramentos da alimentação sanguínea incluem o estresse da picada, que leva a menor ganho de peso e produção de leite, e à infecção por patógenos que S. calcitrans transmite mecanicamente. Os prejuízos anuais causados pela mosca-dos-estábulos no Brasil são estimados em 340 milhões de dólares. Considerando a importância desse organismo e os prejuízos acarretados por ele nos ambientes de criação é cada vez mais importante entender diversos aspectos da biologia de S. calcitrans. No presente trabalho são apresentados diferentes assuntos relacionados a esse inseto. O capítulo I se dedica a descrever o estabelecimento de uma colônia de S. calcitrans, com o objetivo de gerar insetos em condições de laboratório que pudessem ser utilizados para experimentos controlados. O capítulo II descreve a morfologia das glândulas salivares da mosca a partir de técnicas de microscopia óptica, histologia e ultraestrutura, e também a composição lipídica. Além disso, foi realizado teste da atividade de stomoxina, um peptídeo antimicrobiano da saliva de S. calcitrans contra Leishmania amazonensis e Trypanosoma cruzi. No capítulo III buscamos entender como S. calcitrans interage com patógenos. Esse é um passo importante para esclarecer a dinâmica de transmissão por essa mosca, sendo assim o modelo escolhido foi Leishmania agente etiológico das leishmanioses, doenças com característica antropozoonótica. Leishmania sp. foi capaz de interagir com o intestino de S. calcitrans, mas os mecanismos pelo qual essa ligação ocorre ainda devem ser esclarecidos.por
dc.description.sponsorshipCAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superiorpor
dc.formatapplication/pdf*
dc.languageporpor
dc.publisherUniversidade Federal Rural do Rio de Janeiropor
dc.rightsAcesso Abertopor
dc.subjectColônias de insetopor
dc.subjectsalivapor
dc.subjectvetor mecânicopor
dc.subjectInsect colonieseng
dc.subjectmechanical vectorpor
dc.titleStomoxys calcitrans: estabelecimento de colônia, caracterização da glândula salivar e interação com patógenospor
dc.title.alternativeStomoxys calcitrans: colony establishment, salivary gland characterization and interaction with pathogenseng
dc.typeTesepor
dc.description.abstractOtherStomoxys calcitrans (Diptera), known as stable fly presents great veterinary importance. Males and females feed on blood, a parasitic habit that results in damage to livestock. The consequences of blood feeding include bite stress, which leads to lower weight gain and milk production, and infection with pathogens that S. calcitrans mechanically transmits. The annual economic damage caused by the stable fly in Brazil is estimated at US $ 340 million. Considering the importance of this organism and the damage caused by it in the breeding environments, it is increasingly important to understand different aspects of the biology of S. calcitrans. In the present work, different subjects related to this insect are presented. Chapter I describes the establishment of a colony of S. calcitrans, with the objective of generating insects under laboratory conditions that could be used for controlled experiments. Chapter II describes the fly's salivary glands morphology using optical microscopy, histology, ultrastructure and also lipid composition. In addition the activity of stomoxin, an antimicrobial peptide from S. calcitrans saliva against Leishmania amazonensis and Trypanosoma cruzi. In chapter III we seek to understand how S. calcitrans interacts with pathogens. This is an important step to clarify the dynamics of transmission by this fly, so the model of choice was Leishmania etiologic agent of leishmaniasis, diseases with anthropozoonotic characteristics. Leishmania sp. was able to interact with the intestine of S. calcitrans, but the mechanisms by which this interaction occurs remain yet to be clarified.eng
dc.contributor.advisor1Lima, Patrícia Fampa Negreiros
dc.contributor.advisor1ID651.721.247-72por
dc.contributor.advisor1Latteshttp://lattes.cnpq.br/8327606827760440por
dc.contributor.referee1Lima, Patrícia Fampa Negreiros
dc.contributor.referee2Silva, Claudia Bezerra da
dc.contributor.referee3Mallet, Jacenir Reis dos Santos
dc.contributor.referee4Nepomuceno, Leilane Maria Barcellos
dc.contributor.referee5Cirne, Lilian Cristina de Sousa Oliveira Batista
dc.creator.ID125.365.537-52por
dc.creator.Latteshttp://lattes.cnpq.br/3381527239868582por
dc.publisher.countryBrasilpor
dc.publisher.departmentInstituto de Veterináriapor
dc.publisher.initialsUFRRJpor
dc.publisher.programPrograma de Pós-Graduação em Ciências Veterináriaspor
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